The New York Breast Cancer Study was started in 1996 to identify all the genes responsible for a higher risk of breast cancer among Ashkenazi Jewish women. Between 1996 and 2000, women who experienced a first diagnosis of breast cancer and who identified themselves and all four grandparents as Ashkenazi Jewish were invited to participate. More Ashkenazi Jews Have Gene Defect that Raises Inherited Breast Cancer Risk. An inherited genetic mutation that increases the risk of breast cancer in Jewish women of Eastern European descent is three times more common than previously estimated, according to a study led by researchers at Memorial Sloan-Kettering Cancer Center in New York.
They believed that because breast cancer was clearly both a common and a multifactorial disease, it would be unlikely for any predisposing genes to segregate within specific ethnic or racial groups.43, 44 Moreover, epidemiological studies had not identified Ashkenazi Jewish women as having significantly higher rates of breast cancer.45 – 47 Cited by: 20. Jan 18, 2018 · More News About Inherited Breast Cancer Risk in Ashkenazi Jewish Women. Mutations in the genes BRCA1 and BRCA2 are the most common cause of hereditary breast cancer. Among women of Ashkenazi Jewish heritage, about 11 percent of all breast cancers are caused by one of only three BRCA1 or BRCA2 mutations. These three mutations are called.
This debate is happening in Israel (and not in, say, Japan) because about half of the Jewish population of Israel is of Ashkenazi Jewish descent, tracing their ancestry to Jews from central and eastern Europe. Among this group, genes contributing to breast cancer are .